Composition for preventing the occurrence of cardiovascular event in a patient with multiple risk

Composici6n for use in primary prevention of cardiovascular event in a patient with hypercholesterolemia, wherein the composition comprises acid ethyl ester ° all-cis-5,8,11,14,17-eicosapentaenoic as its effective component and used in combination with an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase, wherein the cardiovascular event is cardiovascular death, fatal myocardial infarction, sudden cardiac death, nonfatal myocardial infarction, cardiovascular angioplasty, or new aparici6n of angina at rest and exercise induced angina, and wherein said patient also has hypertriglyceridemia defined by a value of triglyceride (TG) serum of at least 150 mg / dl and cholesterol low HDL defined by a value of C-HDL less than 40 mg / d1.