An open study of oral flesinoxan, a 5-HT1A receptor agonist, in treatment-resistant depression

Flesinoxan, a full 5-HT1A, receptor agonist, was administered (4–8 mg) to treatment-resistant depressed patients in an open study. Safety and tolerance of the substance appeared satisfactory. Headache, dizziness and nausea were the most frequently reported side effects. The observations suggested th