Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

Gregory W. Goldberg,Wenyan Jiang,David Bikard,Luciano A. Marraffini

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

2014

Gregory W. Goldberg
Wenyan Jiang
David Bikard
Luciano A. Marraffini

The Staphylococcus epidermidis CRISPR-Cas system can prevent lytic infection but tolerate lysogenization by temperate phage through a transcription-dependent DNA targeting mechanism.

Keywords:

CRISPR
Lytic cycle
Staphylococcus epidermidis
Temperateness
Bacteriology
DNA
Lysogenic cycle
Microbiology
Transcription (biology)
Biology
Genetics
Prophage
Genome
Circular bacterial chromosome
Gene

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