Impact of Perioperative Stroke on Mid Term Outcomes after Transcatheter Aortic Valve Replacement

ABSTRACT Background Transcatheter Aortic Valve Replacement (TAVR) has evolved as an alternative therapy to open AVR in most patients with aortic stenosis. Stroke associated with TAVR can be a devastating complication in the short-term, however, little is known regarding mid-term outcomes. Methods All patients undergoing TAVR from 2011-2018 were included. Modified Rankin Scales (mRS) as a measurement of stroke related disability were extracted for patients who had neurologic deficits. Results A total of 51 (4.3%) patients (out of 1193) developed neurologic events (NE) during study period (32 [2.7%] disabling strokes, 19 [1.6%] non-disabling strokes including 5 [0.4%] transient ischemic attacks). Patients sustaining TAVR NEs were older (85.8±4.2 years vs 81.5±7.9 years,p Conclusions Stroke increases short term and mid-term mortality following TAVR. Risk prediction for neurologic events in TAVR could aid framework for patient selection, further improving outcomes.