Apparent molar volume and apparent molar adiabatic compressibility studies of anesthetic molecules in aqueous micelle solutions of CTAB and CTAC as a function of surfactant concentration and temperature

Apparent molar volume and adiabatic compressibility properties of halothane and isoflurane in aqueous micelle solutions of hexadecyltrimethylammonium bromide (CTAB) and chloride (CTAC) have been studied as a function of surfactant concentration and temperature. Specific conductance measurements of the micellar systems in the presence and absence of the additive molecules were used to estimate the effect of the solubilized additives on the apparent degree of micelle dissociation. As well, 1 H T 1 relaxation and chemical shift studies of the micellized surfactant in the absence and presence of the additive were measured in an attempt to obtain complementary data regarding the solubilization sites of the additives in the micellar systems