Application of Echocardiography Information Technology in Monitoring Cardiac Function and Peripheral Neurotoxicity of HPV Patients Infected with Breast Cancer after Chemotherapy

The paper is aimed to investigate the changes in cardiac function and peripheral neurotoxicity caused by postoperative chemotherapy in patients with breast cancer infected with human papillomavirus (HPV) by echocardiogram information technology. 68 patients with breast cancer undergoing anthracycline (ATC) drug chemotherapy were selected as the research subjects. The routine echocardiography was performed before and after each patient's chemotherapy. Also, the two-dimensional speckle ultrasound technology was used to measure the index data of the left ventricular systolic function. It Includes the global longitudinal strain (GLS) value of the left ventricle in each stratified systole, the longitudinal strain (LS) value of the left ventricle of each ventricle section and the left ventricular ejection fraction (LVEF). At the same time, neuropsychological assessment was used to judge the degree of nerve damage caused by chemotherapy. The results showed that Most measurement indexes of the conventional echocardiogram were not statistically significant before and after chemotherapy. The comparative analysis of the two-dimensional strain parameter values of echocardiogram revealed that the longitudinal strain value of the left ventricle endocardial layer was statistically significant before and after chemotherapy. There was also a significant difference in the overall longitudinal strain value and left ventricular ejection fraction of left ventricle systole during and after chemotherapy (P < 0.05). Its index decreased significantly, indicating that there was myocardial damage. The memory and self-cognitive function of breast cancer patients decreased significantly (P < 0.05), but the memory of the control group did not decrease significantly. In conclusion, echocardiogram information technology can effectively monitor changes in cardiac function. Rs-fMRI can monitor the changes in related nerve functions of breast cancer patients after chemotherapy.