Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization.

Yoo Chun Kim,Hans E. Grossniklaus,Henry F. Edelhauser,Mark R. Prausnitz

Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization.

2014

Yoo Chun Kim
Hans E. Grossniklaus
Henry F. Edelhauser
Mark R. Prausnitz

Purpose. This study tested the hypothesis that highly targeted intrastromal delivery of bevacizumab using coated microneedles allows dramatic dose sparing compared with subconjunctival and topical delivery for treatment of corneal neovascularization.

Keywords:

Bevacizumab
Corneal neovascularization
Vascular endothelial growth factor A
Anatomy
Biology
Subconjunctival injection
Surgery
Cornea
Eye drop
Suture (anatomy)
Neovascularization
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