On the copper transfer between dopamine β-monooxygenase and Cu-thionein

Metallothionein saturated with copper is able to donate copper to apodopamine β -monooxygenase. The complete recovery of dopamine β -monooxygenase activity is observed at the molar ratio Cu-thionein/apoenzyme of 25. On the other hand, apothionein accepts copper easily from the holoenzyme.