Profil Laboratorium Ibu Hamil dengan COVID-19 di Rumah Sakit UNS

Pendahuluan: Kasus ibu hamil dengan kondisi COVID-19 terjadi perubahan sistem imun dan luaran kehamilan. Pasien kehamilan dengan COVID-19 membutuhkan tatalaksana yang khusus. Tujuan penelitian untuk mengetahui profil laboratorium ibu hamil dengan COVID-19  di Rumah Sakit UNS. Metode: Penelitian yang dilakukan bersifat observasional analitik. Rancangan penelitian yang digunakan adalah cohort retrospektif . Penelitian ini dilakukan di Rumah Sakit UNS Sukoharjo mulai dari bulan Januari sampai Februari  2021. Kriteria inklusi adalah ibu hamil dengan suspek COVID-19. Data klinis dan laboratorium dibandingkan antara kelompok COVID-19 dan non COVID-19. Uji statistik menggunakan uji t independent dan uji chi square. P bermakna jika p < 0,05. Hasil: Dari  32 pasien ibu hamil suspek COVID-19, 18 terdiagnosis Non COVID-19 dan 14 pasien COVID-19. Rerata usia adalah Non COVID-19 adalah 30,33 + 6,62 tahun, pasien COVID-19 31,36 + 6,57. Peningkatan leukosit lebih banyak didapatkan pada pasien Non COVID-19 (p=0,01), sedangkan neutrofil (p=0,01), NLR (p=0,03) dan lama rawat inap (p=0,01) lebih banyak pada pasien COVID-19 dibandingkan pasien COVID-19.. Kesimpulan: Leukosit, neutrofil, NLR dan lama rawat inap berbeda antara pasien hamil dengan COVID-19 dan Non COVID-19. Kata Kunci: COVID-19, Kehamilan, leukosit, netrofil, NLR, lama rawat inap. ABSTRACT Introduction: In cases of pregnant women with COVID-19 conditions, changes in the immune system and pregnancy outcomes occur. Pregnant patients with COVID-19 need exceptional management. The research objective was to determine the Laboratory Profile for Pregnant Women with COVID-19 at the UNS Hospital. Method: This research is analytic observational. The research design used was a retrospective cohort. This research was conducted at the UNS Hospital from January to February 2021. The inclusion criteria were pregnant women with suspected COVID-19. We compare Demographic and laboratory data between the COVID-19 and non-COVID-19 groups. Statistical test using independent t-test and chi-square test. P is significant if p <0.05. Result: Of the 32 pregnant women patients with suspected COVID-19, 18 were diagnosed with Non-COVID-19 and 14 were COVID-19 patients. The mean age was Non COVID-19 was 30.33 + 6.62 years, for COVID-19 patients 31.36 + 6.57. The increase in leukocytes was more found in Non COVID-19 patients (p = 0.01), while neutrophils (p = 0.01), NLR (p = 0.03) and length of stay (p = 0.01) were more in COVID-19 patients versus COVID-19 patients .. Conclusion: Leukocytes, Neutrophils, NLR, and length of stay differed between pregnant patients  COVID-19 and non-COVID-19. Keywords: COVID-19, Pregnancy, Leukosit, Netrofil, Neutrophils to lymphocyte ratio, length of stay