Исследование состояния перекисного окисления липидов у больных раком вульвы

Comparative analysis of oxidative processes' intensity and of the blood antioxidant system condition in 71 patients with stage I-IV vulvar cancer aged 37-87 years was made. 30 patients were diagnosed with primary cancer, 21 had a relapse and 20 were in the third clinical group (state of remission). Chemiluminescence intensity, catalase and ceruloplasmin activity, content of lipid and protein peroxidation products were studied in blood plasma. Decrease of intensity of free radical processes and lipid peroxidation, restoration of structural and functional condition of erythrocyte membranes take place in remission, while activity of catalase raise, increase of ceruloplasmin content, decrease in activity of superoxide dismutase and increase in activity of glutathione peroxidase are recorded in relapses.