A Novel Model System for Understanding Anticancer Activity of Hypoxia-Activated Prodrugs.

Zhiyuan Sun,Haoqi Zhang,Jin Wu,Fangli Gao,Congcong Zhang,XueYan Hu,Qiqi Liu,Yonghua Wei,Jie Zhuang,Xinglu Huang

A Novel Model System for Understanding Anticancer Activity of Hypoxia-Activated Prodrugs.

2020

Zhiyuan Sun
Haoqi Zhang
Jin Wu
Fangli Gao
Congcong Zhang
XueYan Hu
Qiqi Liu
Yonghua Wei
Jie Zhuang
Xinglu Huang

Reports on the comprehensive factors for design considerations of hypoxia-activated prodrugs (HAPs) are rare. We introduced a new model system composed of a series of highly water-soluble HAPs, pro...

Keywords:

Drug delivery
model system
Hypoxia (medical)
Prodrug
Biochemistry
hypoxia activated prodrug
Chemistry

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