P-0168 Epidemiology of Gallbladder Cancer in Algeria

ABSTRACT Introduction Gallbladder cancer incidence is higher in women than in men in most areas of the world. It is a relatively rare neoplasm, Diagnosis is generally made when the cancer is already in advanced stages, and prognosis for survival is less than 5 years in 90% of cases. This study was designed to provide up-dated incidence figures for Gallbladder cancer in Setif at the period 1986-2008 adjusting for the effect of age, sex, and period of diagnosis and the geographical distribution. These datas are compared with standardized rates of Cancer Registries in Five Continents. Methods Cancer registry represents a data source. Cancer morphology and topography are coded in accordance of the international classification of diseases for oncology manual (ICD-O, the third edition). Results In Setif, Algeria, gallbladder cancer ranked third in the female population with the standardized incidence rates 8.1 /100.000 persons year for representing 8.9 % of all cases among women. The Gallbladder cancer touch the young woman from the age of 35 years to increase gradually with the age and reach a maximum in 70-74 years then the incidence increases quickly from 85 years with a median age at 62 years old. Conclusion Gallbladder cancer is an important public health problem in Algeria. Incidence and mortality have been declining in Algeria the last few decades, mainly due to the increasing frequency of cholecystectomy. More than 50% of new cases are the young women whose age is inferior at 50 years. It represents the second cause of mortality at women in Algeria it accounts 6000 deaths each year.