Stereospecific friedel-crafts alkylation of benzene with 4-mesyloxy-L-prolines. A new synthesis of 4-phenylprolines

Abstract The reaction of benzene with cis - and trans -N-benzoyl-4-mesyloxy-L-proline ( 11 and 12 ) in the presence of AlCl 3 stereospecifically produces the corresponding trans - and cis -4-phenylproline derivatives.