Evaluation of Different Steroid Nasal Spray in Chronic Rhinosinusitis: A Comparative Study

Aim: In this study, we compared the efficacy of fluticasone propionate (FP) and mometasonefuroate (MF) nasal sprays in the treatment of allergic rhinitis based on total nasal symptom score (TNSS) questionnaire. Methodology: For this study, 60 chronic rhinitis patients based on inclusion criteria were randomly assigned to two groups: FP and MF groups. FP group received 200 μg dose of FP nasal spray (2 sprays/nostril) daily and the MF group received 100 mg dose of MF nasal spray (2 sprays/nostril) daily for 8 weeks. The effects of the two agents were compared based on TNSS questionnaire in 0, 4 and 8 weeks after the beginning of the treatment. Results: Patients in both groups exhibited significant improvement in their TNSS (P Value 0.05). Conclusion: In conclusion, FP and MF are significantly effective in relieving of chronic rhinitis symptoms. Even though, the difference between the two is not significant for 8 weeks therapy.