Open image in new window Synthesis of 5-hydroxyfuran-2(5H)-one derivatives (microreview)

In this microreview, we describe methods for the synthesis of 5-hydroxyfuran-2(5H)-one derivatives, which have been published over the last 5 years. The main routes for the preparation of 5-hydroxyfuran-2(5H)-one derivatives include transformations of 2-oxocarboxylic acids, formylation or carboxylation of functionalized aromatic (heterocyclic) compounds, as well as synthetic modifications of furan derivatives.