Gene targeting of HPV18 E6 and E7 synchronously by non-viral transfection of CRISPR/Cas9 system in cervical cancer

Kaijian Ling,Leiyan Yang,Neng Yang,Mengyue Chen,Yanzhou Wang,Shi Liang,Yudi Li,Lupin Jiang,Ping Yan,Zhiqing Liang

Gene targeting of HPV18 E6 and E7 synchronously by non-viral transfection of CRISPR/Cas9 system in cervical cancer

2020

Kaijian Ling
Leiyan Yang
Neng Yang
Mengyue Chen
Yanzhou Wang
Shi Liang
Yudi Li
Lupin Jiang
Ping Yan
Zhiqing Liang

High-risk human papillomavirus (HPV) E6 and E7 genes display vital oncogenic properties in cervical cancer. Eliminating HPV driver gene or lose-of-function by the clustered regularly interspaced sh...

Keywords:

Gene targeting
Virology
human papillomavirus
CRISPR
Cervical cancer
Transfection
Gene
Biology
Loss function

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