Memantine hydrochloride synthetic method
2013
The invention relates to a memantine hydrochloride synthesis method which is as follows: heating formula (II) compound in an alcohol solution of potassium hydroxide for salifying with hydrogen chloride to obtain the formula (I) compound. The method yield reaches 90%, the purity reaches 99.9% (GC), energy consumption is low, reaction solvent can be rectified and recovered, environmental pollution is avoided, and the method is a green process for preparing memantine hydrochloride.
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