Hemorrhage of hepatocellular adenoma: a complication that can be treated by conservative management without surgery

Abstract Background Hemorrhage is the main complication of hepatocellular adenoma (HCA). The aim of this study was to describe a single center's evolving management of patients with hemorrhagic HCA. Method Between 1990 and 2013, all patients with hemorrhagic HCA were included. During the study period, the management evolved from urgent surgery (period  2010) delayed resection. Results A total of 56 patients were identified. The median (range) size of HCA and the hematoma was 80 mm (35–160) and 50 mm (10–160). Patients were treated by urgent resection (group 1, n = 6), delayed resection with or without embolization (group 2, n = 43) and systematic embolization without surgery (group 3, n = 7). Embolization was performed in 0/6, 15/43 and 7/7 in groups 1, 2 and 3. Urgent resection was associated with higher morbidity (p   60% (p = 0.046) and a cystic non-viable lesion before surgery (p  Conclusion Hemodynamic stability can be achieved in patients presenting with hemorrhagic HCA by none surgical means. Subsequent surgery can be completely avoided with such an approach in up to 40% of patients.