Regiospecific and site-selective C–H allylation of phenols with vinyldiazo compounds catalyzed by In(III)

Metal-catalyzed C–H functionalization is one of the most effective methods to form a C–C bond. We herein report a highly regiospecific, site-selective, and C–H chemoselective substitution reaction of phenols with alkenyl diazo compounds catalyzed by commercially available and low-cost In(OTf)3. The reactions of aryl or alkyl substituted vinyldiazoacetates provided the corresponding phenol-allylation products in different regioselective and site-selective manners.