Risk assessment by physicians and by the poison center: Are nondrug exposures handled too actively?

Background: The study was intended to evaluate the possible impact of poison center advice on physicians' treatment and referral of nondrug exposures.Methods: Doctors seeking advice on nondrug poisoning were asked for their management plan before any recommendations were given. The proportions of cases in different treatment and referral categories were compared to the poison center recommendations. Rate ratios were used as effect measure.Results: A total of 175 cases were included in the study. For 90% of these, the exposure was estimated by the poison center to be of no or minor risk. The inquiring physicians had intended to treat 43 more cases than the poison center recommended, rate ratios: 1.6 (95% CI: 1.3–2.0). The most marked difference was for treatment by gastrointestinal decontamination, rate ratios: 5.0 (95% CI: 2.5–9.8). For referral, 42 more cases would have been observed in a stationary hospital unit, rate ratios: 2.3 (95% CI: 1.6–3.3) and 28 excess cases would have been observed in an outpa...