Pegylated recombinant human arginase (rhArg-peg 5000mw) has in vitro and in vivo anti-proliferative potential and apoptotic activities in human hepatocellular varcinoma (HCC)

3179 Background: Our group has previously reported that in vivo arginine depletion with rhArg-peg is safe and that it has marked anti-HCC activities. We report here the combined in vivo anti-tumor ...