Clinical analysis on pathogenic bacteria and clinical feature of infectious endophthalmitis after cataract surgery

Objective To analyze the clinical feature and pathogenic bacteria of infectious endophthalmitis after cataract surgery. Methods The data of 87 cases with infectious endophthalmitis after cataract surgery from Jan.2013 to Dec. 2016 were collected and analyzed retrospectively. Results The rate of endophthalmitis after cataract surgery was 0.21%, which was affected by age, type of cataract, whether combined with other ocular diseases and systemic diseases. Of the 87 cases, 84 cases were acute endophthalmitis.The onset time of the disease was 1-30 days after surgery, average (6.57±6.83) days, and the peak period of the disease was 10 days after operation. The positive rate of bacterial culture was 39.44%, of which the highest positive rate bacterial culture in vitreous was 45.83%.Staphylococcus epidermidis occupyed for 75.00%, it was sensitive to Vancomycin, Linezolid and Rifampin, low sensitive to Macrolides, and sensitivity to other drugs ranged from 30.00% to 75.00%.The endophthalmitis of 71 patients(81.61%) were controlled after vitrectomy and / or intravitreal injections of antibiotics, and the vision was restored. Conclusion There are many risk factors associated infectious endophthalmitis after cataract surgery, and most of them are acute episodes.As soon as possible to clear the specimen of pathogenic bacteria has important significance to guide drug therapy.The vitrectomy and / or intravitreal injections of antibiotics are key factors to control endophthalmitis and improve the prognosis. Key words: Cataract; Endophthalmitis, infectious; Pathogenic bacteria; Microbial sensitivity tests