BIOLOGICAL AGE OF MEN ­ ROTATION WORKERS OF ARCTIC, RESIDENTS OF THE SOUTHERN PART OF TYUMEN REGION ­ A COMPARATIVE STUDY

Objective. To study circadian rhythms of the cardiovascular and respiratory system variables and to evaluate biological age in people of adult men, involved in Arctic Sojourn vs. residents of the of the Tyumen region South. Methods. Functional indices of the cardiovascular system and external respiration were studied four times a day at 8, 12, 16 and 20 hours in 34 men (mean age 30.1 ± 0.8 years), long time working in the village of Kharasavey (The Arctic group), and 30 men aged 37.0 ± 1.0 years living and working in the South of the Tyumen region (Tyumen Control group). Biological age was estimated in the both groups on the basis of chronobiological approach. Results. Circadian rhythms of the cardiovascular and respiratory system indices in men in the Control group were more robust than that of the Arctic group. This was manifested in higher values of amplitudes and more stable acrophases. Diurnal rhythm amplitudes of the number of variables (systolic blood pressure, pulse pressure, vital capacity of lungs) of the Control group were significantly higher than those of the Arctic group. Conclusions. The structure of biological rhythms of physiological parameters (especially amplitude) is a sensitive indicator of the functional state of humans and can be successfully used to assess biological age. The biological age of the Arctic group men more profoundly exceeded chronological age compared to men working in the South region.