Highly Efficient Synthesis of 5-Benzyl-3-aminoindazoles.
2009
A rapid and efficient procedure for the preparation of 5-benzyl-3-aminoindazoles 1 is reported. Key intermediates are fluoro-cyano diarylmethanes 2 which have been obtained by two different synthetic approaches. Benefits of these methods result from the use of commercially available starting materials and practical experimental conditions that allow easy scale-up.
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