The biorhythmology of primary and superinvasive opisthorchiasis. The seasonal changes in the circadian activity of the portal (regional) lymph node in golden hamsters

: 540 male golden hamsters were divided into 3 groups: I--free from invasion, II--once infected, III--repeatedly infected. Diurnal activity of portal lymph node immunocompetent cells was investigated in spring, autumn and winter at 3, 7, 11 a. m. and 3, 7, 11 p. m Peculiarities of diurnal immunocompetent cell activity at on acute opisthorchiasis stage, depending upon a season invasion frequency is determined by immunoreactivity level. Eosinophilic and lymphocytic reactions and the ratio of mitotic activity to degenerative elements are the lymph-node immunocompetence indices.