The benefit of using synergistic mixtures of preservatives

The patents DE 4026756 (1) and US 5670160 (2) describe the synergistic mixture of different organic acids in combination with different alcohols and poly(hexamethylene biguanide) salts. This paper scrutinizes the advantage of a commercially available mixture using this combination for the preservation of cosmetics and toiletries. The amount of polyaminopropyl biguanide in this formulated product is far below its normally recommended use concentration, it acts together with the Ethylhexylglycerin as a preservative enhancer.