Yıllara göre duodenum ve mide ülserli olguların ve bu olgulardaki Helikobakter pilori sıklığının irdelenmesi: Retrospektif 10 yıllık irdeleme

Background and aims: The aim of this study was to evaluate the frequency of the duodenal and gastric ulcer in cases underwent to upper gastrointestinal endoscopy according to each year, and to evaluate the frequency of Helicobacter pylori in these cases with ulcers. Material and Methods: All of the upper gastrointestinal endoscopy reports from archieve of Department of Gastroenterology, Ege University Medical School between July-1996 and June-2005 were searched. The frequency of the cases with duodenal and gastric ulcer were analyzed according to each year and to the 5-year periods. The presence of Helicobacter pylori was diagnosed by rapid urease test. All of the cases with duodenal and gastric ulcer were evaluated in order to detect the frequency of ulcer, and only cases with urease test result were included into the assessment in order to detect the frequency of Helicobacter pylori. Results: Overall, 35957 endoscopies were performed betweeen 1996 and 2005. Of these, duodenal ulcer was found in 4281 (11.9%), and gastric ulcer in 1677 (4.6%) cases. There was no difference in gastric ulcer frequencies according to each year and to the 5-year periods, however, a decrease was observed in frequency of duodenal ulcer. Helicobacter pylori frequency in duodenal ulcer cases decreased according to each year and to the 5-year periods. In gastric ulcer cases, although there was no difference in Helicobacter pylori frequency according to each year, Helicobacter pylori frequency was found to be lower in the latter 5-year period. Conclusions: Although there was no difference in frequency of gastric ulcer in the latter 5-year period, a decrease was observed in frequency of Helicobacter pylori in these cases. This may be explained by an increase in the use of non steroidal anti inflammatory drugs which play an important role in gastric ulcer etiopathogenesis. On the other hand, there was a decrease in frequency of duodenal ulcer and also frequency of Helicobacter pylori in these cases. This may be explained by the eradication of Helicobacter pylori.