CT-based temperature monitoring during hepatic RF ablation: feasibility in an animal model.

Purpose: The aim of this paper was to establish non-invasive CT-based temperature monitoring during hepatic radiofrequency (RF) ablation in an ex vivo porcine model followed by transfer of the technique into a feasibility in vivo experiment.Materials and methods: Bipolar RF ablations were performed in 10 specimens of porcine liver. Parallel to the needle-shaped RF applicator three optical temperature probes were inserted into the liver specimens at fixed distances of 5, 10 and 15 mm from the RF probe. During energy application (20 W) unenhanced sequential MSCT scans were acquired using the following scan protocol: 140 kV tube voltage, 300 mAs/rotation tube current time product, collimation 24 × 1.2 mm, rotation time 0.5 s. Axial image data was reconstructed using a soft tissue convolution kernel. Temperature data was recorded during every CT scan. Using a circular 0.5 cm2 region of interest local CT values were measured at the tips of the temperature probes and matched with the measured temperatures. Regr...