Enhancer for the synthesis of anti-AIDS drugs intermediates cobicistat
2014
In one aspect the present invention discloses a method for the synthesis of novel intermediates for synthesizing compounds for anti-HIV enhancer cobicistat I, on the other hand discloses a synthesis of the compound I (2R, 5R) -1,6- diphenyl the method of 2,5-hexamethylene diamine. This new synthesis of intermediate compound I (2R, 5R) -1,6-line method phenyl 2,5-diamine having less steps, production conditions, easy to operate, low cost of production, and the purity of the product high to meet the requirements of high-quality pharmaceutical products.
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