Sociodemographic characteristics and clinical outcomes among patients with comorbid alcohol dependence and depressive spectrum disorders

Introduction The accelerated development of substance dependence with social disadaptation and delinquent behavior, which is associated with the integration of pathological processes addictive and mental pathology, is observed in most patients with comorbid mental disorders. Aims We evaluated the association of sociodemographic characteristics with clinical outcomes among patients with comorbidity of alcohol dependence and depression. Objectives To study the structure and clinical features of depressive spectrum disorders with comorbid alcohol dependence among males aged 18–60. Data were collected at the Khabarovsk territorial psychiatric clinic, and all participants provided written informed consent prior to participation. Participants in the current study consisted of 89 males with comorbid alcohol dependence and depression (ICD-10 criteria). Methods The present study based on clinical examination and interview, including data of demographic characteristics, family background and remission. Logistic regression was used to evaluate the associations of interest. Results Analyses showed that risk of relapse was higher among males with low education and income level ( r =0.65; r =0.55), family destruction until puberty ( r =0.76), parental alcohol misuse ( r =0.74), authoritarian parenting style in childhood ( r =0.55), conflict relationships with spouse ( r =0.80), "conflict" dominant motivation for abstinence ( r =0.77), mood swings ( r =0.74) and absence of treatment for depression ( r =0.80). Conclusions Integrative approach to treatment of patients with comorbid alcohol dependence and depressive spectrum disorders should take into consideration sociodemographic characteristics.