MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

Lea H. Gregersen,Anders Jacobsen,Lisa B. Frankel,Jiayu Wen,Anders Krogh,Anders H. Lund

MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

2010

Lea H. Gregersen
Anders Jacobsen
Lisa B. Frankel
Jiayu Wen
Anders Krogh
Anders H. Lund

Background MicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in tumorigenesis. miR-145 is reported to be down-regulated in several cancers, but knowledge of its targets in colon cancer remains limited.

Keywords:

Regulation of gene expression
DNA microarray
Three prime untranslated region
Colorectal cancer
Transfection
Cell cycle
microRNA
Carcinogenesis
Cancer research
Biology
Cancer
MiRNA binding

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