Application of magnetic compression technique in gastrojejunostomy: an experimental study

Objective To explore the feasibility, safety and effectiveness of Magnetic compression anastomosis (MCA) for gastrojejunostomy in rabbits. Methods 8 rabbits were subjected to gastric-jejunal anastomosis by magnetic compression according to the established surgical operation path. After 48 hours of magnet extubation, 4 rabbits were randomly selected to observe the anastomosis and cut its tissues for hematoxylin and eosin (HE) and Masson staining. The remaining 4 rabbits were performed pyloric ligation, and 14 days later, iodohexol angiography was performed to observe the patency and leakage of the anastomosis. Results All the 8 rabbits were successfully treated with gastric-jejunal anastomosis. The animals survived well and the magnets were discharged within 8-12 days. The anastomosis healed well, and the surrounding inflammatory reaction was mild without leakage. After ligation, 1 rabbit died due to anastomotic leakage, the rest survived well, and radiography showed good patency. Conclusion MCA can safely realize the anastomosis between stomach and jejunum and solve the problem of pyloric obstruction, which is expected to develop into a new anastomosis of digestive tract. Key words: Magnetic compression anastomosis; Gastrojejunostomy; Digestive tract reconstruction; Pyloric obstruction