Anti-Mpl antibody

Get and purified anti-human Mpl antibodies were purified anti human Mpl diabody and anti-human Mpl sc (Fv) 2 by genetic engineering techniques. Anti-human Mpl sc the (Fv) 2 was able to be humanized further. Evaluation of the Diabody and sc (Fv) 2 of TPO-like agonist activity, to anti-human Mpl antibodies, Diabody and sc (Fv) 2 showed a high agonistic activity, human TPO activity equal to or greater than that of the natural ligand It was found to exhibit.