The rationale behind hypofractionated high-dose intensity-modulated radiotherapy in patients with localized prostate cancer: short review.

: The use of improved technology has fostered increasing interest in hypofractionated radiation therapy for prostate cancer. There also is convincing evidence that an unusual aspect of prostate cancer radiobiology allow a different approach to dose escalation that is radiobiological in nature. The aim of this paper is to explain the rationale behind hypofractionated high-dose intensity-modulated radiotherapy in patients with localized prostate cancer.