ANTISNAKE VENOM SERUM (ASVS)

Snakebite is a common medical emergency in the tropical region causing Multisystemic Involvement. Treatment with Antisnake venom (ASV) is life saving yet dangerous. ASV usage remains a very risky, because the serum being heterologous and liable to cause sensitivity reactions in occasional patients. The world of ASV production is currently a gloomy place to visit. The Methodology of Antivenom serum preparation has not advanced much since its discovery; Procedures of Immunisation and Purification have been improved using Modern Technology. The Improved Purification of Antivenom by using Immunoglobulin fragments has leads to increased tolerance, efficiency and safety of Antivenom. The future of Immunotherapy seems to be good. This Article gives Prominence to ASV production, purification and quality control, Dose and Administration of ASV, Incidence of Adverse Reactions and its proposed Treatment.