A Convenient One-Pot Synthesis of β -(Trifluoromethyl)allylaminophosphonic and Benzylaminophosphonic Acids

The reductive condensation of aminoalkylphosphonic acids with β -chloro- or β -ethylthio-(β -trifluoromethyl)acroleins leads to secondary (trifluoromethyl)allylaminophosphonic acids in moderate to good yields. The method appears to be useful for the preparation of benzylaminophosphonic acids.