Complicações Orais em Pacientes em Tratamento Quimioterápico na Unacon, no município de Itajaí/SC

2011 
Chemotherapy affects cells with high mitotic index. Lesions in the oral cavity are the most frequent complication of antineoplastic chemotherapy, because of the high sensitivity of oral tissues and structures to the toxic effects of the chemotherapics. The objective of this work was to register the most common oral complications found in patients undergoing to cancer chemotherapy, determining the frequency of the lesion and the possible interaction with the medication in use. This work was conducted at CEPON (Oncological Center Care), in Itajai (SC), Brazil. Patients’ reports were analyzed and personal data, therapeutic plan and the type of the tumor information were registered. An oral clinical examination was performed to detect buccal manifestations. The data were registered by the distributing the frequency of each episode in accordance with age, gender, and therapeutic modality. The results showed that the most frequent gender was female (60%); in both genders, the age was over 50 years (57,8%); breast cancer was the most incident tumor (11 episodes); oral manifestations found were xerostomy (46 episodes), aphtha (2 episodes), herpes simplex (2 episodes) and candidiases (1 episode). In conclusion the females older than 50 years were the most affected. Most patients had some oral manifestation with a highest incidence of oral dryness, and it was related with many different chemotherapics, being a xerostomy-induced medication.
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