GSTA3 regulates TGF-β1-induced renal interstitial fibrosis in NRK-52E cells as a component of the PI3K–Keap1/Nrf2 pathway:

Yun Xiao,Zhiwei Zhang,Yingyu Fu,Huizhi Shan,Sini Cui,Jun Wu

GSTA3 regulates TGF-β1-induced renal interstitial fibrosis in NRK-52E cells as a component of the PI3K–Keap1/Nrf2 pathway:

2019

Yun Xiao
Zhiwei Zhang
Yingyu Fu
Huizhi Shan
Sini Cui
Jun Wu

ObjectiveTo evaluate the effect of GSTA3 within the PI3K–Keap1/Nrf2 pathway in renal interstitial fibrosis (RIF).MethodsAn in vitro RIF model with TGF-β1 stimulation in NRK-52E cells was establishe...

Keywords:

KEAP1
PI3K/AKT/mTOR pathway
Diabetes mellitus
Anesthesia
Antioxidant
In vitro
Stimulation
Cancer research
Transforming growth factor
Medicine
Reactive oxygen species

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