Collagenolytic protease preparations from invertebrates: experimental study of acute and chronic toxicity.
2000
Toxicity of active matter of new structure-destroying enzyme preparations containing a complex of collagenolytic proteases from invertebrates (Collagenase from hydrobionts, Polycollagenase-K, Fermenkol) was studied. The absence of acute toxicity in skin application is proved, and LD50 for intraperitoneal administration to mice and rats were determined. A long-term treatment with clinical doses under various types of application does not affect body weight gain, biochemical indices of the plasma, ECG, diuresis, and urine content.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
3
References
4
Citations
NaN
KQI