Long Survival after Resection of Small Cell Carcinoma of the Pancreas with Synchronous Adenocarcinoma of the Ampulla of Vater

Small cell carcinoma of the pancreas is very rare and the patient usually died within 1 year after diagnosis. We reported an unusual case with small cell neuroendocrine carcinoma of the pancreas and a synchronous moderately differentiated adenocarcinoma of the ampulla of Vater in a 44-year-old male, who was successfully treated with pylorus-preserving pancreaticoduodenectomy and post-operative cisplatin-based chemoradiation therapy. The follow-up data showed no evidence of recurrence and the patient is in a good health condition at 117 months after the surgery.