Zinc deficiency up-regulates ET-1 mediated secretion and endothelial cell migration through nuclear HIF-1 translocation

Jessica Morand,Anne Briançon-Marjollet,Emeline Lemarié,Brigitte Gonthier,Josiane Arnaud,Irina Korichneva,Diane Godin Ribuot

Zinc deficiency up-regulates ET-1 mediated secretion and endothelial cell migration through nuclear HIF-1 translocation

2019

Jessica Morand
Anne Briançon-Marjollet
Emeline Lemarié
Brigitte Gonthier
Josiane Arnaud
Irina Korichneva
Diane Godin Ribuot

Background and objective. Zinc is involved in the expression and function of various transcription factors including the hypoxia-inducible factor-1 (HIF-1). HIF-1 and its target gene endothelin-1 (...

Keywords:

Secretion
Gene
Endothelin 1
Transcription factor
Molecular biology
Zinc
Chromosomal translocation
Biology
Endothelial stem cell
target gene
Endothelin secretion
Endothelin receptor
Hypoxia-Inducible Factor 1

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