Neoadjuvant Chemotherapy and Nipple-Sparing Mastectomy: Timing and Postoperative Complications

Background As the demand for nipple-sparing mastectomy (NSM) increases and surgeons expand the eligibility criteria, a subset of patients may become candidates following neoadjuvant chemotherapy (NACT). However, the impact of NACT on postoperative complications remains unclear as the current literature is discordant.