Comparative study of community-acquired pneumonia between diabetic and nondiabetic patients with hyperglycemia
2012
AIM: To study the differences in clinical presentation and evolution of community acquired pneumonia (CAP) between patients with known-diabetes and non-diabetic but with hyperglycemia status (HG) at hospital admission.
METHODS: We performed a prospective, observational study of patients admitted to Pneumology department consecutively with a diagnosis of CAP. The plasma glucose levels were measured on admission and patients were divided into two groups: diabetic patients and non-diabetic with HG. We consider HG when plasma glucose level =>200mg/dl. We studied different variables, included severe clinical course (mortality and/or septic shock and/or invasive mechanical ventilation (IMV) during hospital stay.
RESULTS: we studied 1389 patients, 274 were known diabetic and 53 (3,8%) were non-diabetic with HG.
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table 1
CONCLUSIONS: 1.- Non-diabetic patients with HG had a more severe clinical course comparing to known-diabetic, althoug mortality was similar. 2.- Non-diabetic patients with HG had more respiratory comorbidities, reached clinical stability later, had a higher admission to ICU and needed more IMV, with a longer hospital stay. 3.- 4% of patients admitted with a CAP had a not-known HG.
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