Rac1 functions downstream of miR-142 in regulation of erythropoiesis

Hematopoietic-specific miR-142 is a critical regulator of various blood cell lineages including CD4+ dendritic cells[1][1] and platelet biogenesis in megakaryocytes.[2][2] Furthermore, we recently reported that miR-142 is required in order to maintain the biconcave shape of erythrocytes, their