T cell epitope mapping of secukinumab and ixekizumab in healthy donors

Sebastian Spindeldreher,Anette Karle,Evelyne Correia,Maxime Tenon,Sascha Gottlieb,Thomas Huber,Bernard Maillère,Frank Kolbinger

T cell epitope mapping of secukinumab and ixekizumab in healthy donors

2020

Sebastian Spindeldreher
Anette Karle
Evelyne Correia
Maxime Tenon
Sascha Gottlieb
Thomas Huber
Bernard Maillère
Frank Kolbinger

ABSTRACTSecukinumab, a human monoclonal antibody that selectively neutralizes IL-17A, has consistently shown low anti-drug antibody responses in patients with psoriasis, psoriatic arthritis, and an...

Keywords:

Psoriatic arthritis
Monoclonal antibody
Immunology
Psoriasis
Secukinumab
Ixekizumab
Antibody
Biology
Epitope mapping
Immunogenicity
T cell

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