Mouse models for the Study of Fracture Healing and Bone Regeneration

Fragility fractures represent one of the major problems associated with osteoporosis. While in the mid-1990s about half a million hospital admissions in the United States were due to osteoporotic fractures, this number will triple until 2040. Of interest, already in 1995, the direct costs produced by osteoporotic fractures were more than US$14 billion, whereas the indirect costs are estimated to be up to five times higher.