Alkaline Phosphatase Activity and Endotoxemia after Infant Cardiothoracic Surgery

ABSTRACTObjective:Infant cardiopulmonary bypass (CPB) increases intestinal permeability leading to endotoxemia. Alkaline phosphatase (AP) reduces endotoxin toxicity in vitro but its effects on endotoxemia in human disease are poorly understood. We assessed the association between serum AP activity a