The equivalent bronchodilator effects of salbutamol formulated in chlorofluorocarbon and hydrofluoroalkane-134a metered dose inhalers on the histamine-induced pulmonary response in dogs.

Mari Nogami-Itoh,Ikuhisa Yakuo,David M. Hammerbeck,Richard L. Miller,Kunihiko Takeyama

The equivalent bronchodilator effects of salbutamol formulated in chlorofluorocarbon and hydrofluoroalkane-134a metered dose inhalers on the histamine-induced pulmonary response in dogs.

1997

Mari Nogami-Itoh
Ikuhisa Yakuo
David M. Hammerbeck
Richard L. Miller
Kunihiko Takeyama

Purpose. The bronchodilator effect of salbutamol formulated in hydrofluoroalkane-134a (HFA-134a), a Chlorofluorocarbon (CFC)-free propellant for metered dose inhalation (MDI) devices, was compared with that of salbutamol formulated in CFC in anesthetized dogs.

Keywords:

Metered-dose inhaler
Salbutamol
Histamine
Inhalation
Dosage form
Chlorofluorocarbon
Anesthesia
Hydrofluoroalkane-134a
Chemistry
Pharmacology
Bronchodilator
Bronchodilator Effect

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