Clinically Pertinent Manganese Oxide/Polyoxytyramine/Reduced Graphene Oxide Nanocomposite for Voltammetric Detection of Salivary and Urinary Arsenic

Arsenic (AsIII), a notorious environmental hazard poses threat to the lives of several hundred million people. Notwithstanding radical developments of AsIII detection in water, a fast, simple and sensitive electrochemical process with lower detection limit for the quantification of AsIII in saliva and urine samples has scarcely ever been tried. Here, we have detected the poisoning due to AsIII in the saliva and urine samples of tobacco-chewers/smokers using a novel one-pot synthesized MnO2/polyoxytyramine/rGO nanocomposite. The composite was characterized by various analytical techniques such as UV–Vis. and FT-IR spectroscopic analyses, XRD, SEM, TEM, EDAX and elemental mapping analyses. The proposed AsIII quantification system has a wide linearity range (0.01–0.900 ppb) and the lowest detection limit (42 parts per trillion).