RETRACTED ARTICLE: Foxp3 rs2294021 polymorphism contributes to the susceptibility to breast carcinoma
2010
Objective
Foxp3, the main regulator of Treg (regulatory T) cells, is down-regulated in breast carcinoma and other cancers. The rs2294021 Foxp3 polymorphism contributes to Foxp3 down-regulation, thereby weakens its tumor suppressing activity. The aim of our study was to evaluate the potential influence of Foxp3 polymorphism on breast cancer, we conducted a case-control study in Han Chinese women.
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